Nucleofill Medium is an innovative polynucleotide-based injectable developed to regenerate and revitalise ageing skin through biological stimulation rather than volumisation. Formulated with highly purified polynucleotides, it works by activating fibroblasts, encouraging collagen and elastin synthesis, and restoring the skin’s natural hydration and elasticity.
Designed for patients with mild to moderate skin laxity, Nucleofill Medium improves skin density and texture while providing antioxidant protection against free radical damage. The treatment enhances skin quality from within, delivering a firmer, smoother and more radiant complexion without altering natural facial contours.
Its regenerative properties make it suitable for standalone skin rejuvenation or as part of combination aesthetic treatment protocols.
Key Benefits
- High-purity polynucleotide injectable
- Stimulates collagen and elastin production
- Improves skin firmness and elasticity
- Deeply hydrates and revitalises the skin
- Supports fibroblast activity and tissue regeneration
- Provides antioxidant protection
- Improves skin tone and texture
- Reduces the appearance of fine lines
- Suitable for moderate skin ageing
- CE-marked medical device
- Professional use only
Indications
- Mild to moderate skin laxity
- Fine lines and wrinkles
- Dehydrated skin
- Dull complexion
- Loss of skin elasticity
- Uneven skin texture
- Facial rejuvenation
- Neck and décolleté rejuvenation
- Hand rejuvenation
Product Specifications
- Contents: 1 × 1.5ml pre-filled syringe
- Active Ingredient: Highly purified polynucleotides
- Volume: 1.5ml
- Treatment Areas: Face, neck, décolleté and hands
- Professional Use Only
Box Contents
- 1 × 1.5ml sterile pre-filled syringe
- Sterile packaging
- Manufacturer’s instructions for use
Professional Use Only
Nucleofill Medium is intended for use by qualified medical professionals trained in aesthetic injectable procedures. Treatment should only be performed following an appropriate patient consultation and in accordance with the manufacturer’s instructions for use.













Laura Arnold (Verified Customer) –
Fast and efficient as always. Thankyou Team 🙂